Central nervous system complications following Hanta virus cardiopulmonary syndrome.

摘要

Hanta viruses are a family of human pathogens, comprising at least 16 different serotypes. The serotype Puumala, most prevalent in western and central Europe, causes hemorrhagic fever with renal syndrome (HFRS). In contrast, serotypes prevalent in the New World (Sin Nombre, Andes) cause a febrile illness, with severe pulmonary and cardiac compromise (Hanta virus cardiopulmonary syndrome (HCPS)). Review of 811 HFRS cases found that only 1% developed severe central nervous system (CNS) complications (Alexeyev and Morozov, 1995). To our knowledge, neurological complications from New World Hanta infection have not been reported. Acute disseminated encenhalomvelitis (ADEM).