Metallic nanostructures assembled by DNA and related applications in surface-enhancement Raman scattering (SERS) detection

摘要

This review highlights recent advanced researches on the assembly of various metallic nanostructures by oligonucleotide and plasmid DNA. The obtained DNA-nanoconjugates show many unique and attractive properties, while this review focuses on their properties related to SERS detection. The applications of DNA-based assemblies in SERS detections were fully commented upon, for the detection of DNA, proteins, small molecules, and metallic ions. Finally, a concluding section is given, which covers the challenges and scope for DNA assembled nanostructures as well as for the DNA assemblies-related SERS detections.