Synthesis and properties of the metallo-supramolecular polymer hydrogel poly[methyl vinyl ether-att-mono-sodium maleate] AgNO3: Ag~+/Cu~(2+) ion exchange and effective antibacterial activity

摘要

The commercial polymeric anhydride polytmethyl vinyl ether-alt-maleic anhydride) (PVM/MA) is converted by reaction with NaOH to give polytmethyl vinyl ether-a/t-mono-sodium maleate) (PVM/Na-MA). By addition of AgNOs-solution, the formation of the silver(i) supramolecular polymer hydrogel polytmethyl vinyl ether-a/f-mono-sodium maleate]-AgNO3 is reported. Freeze-dried samples of the hydrogel show a mesoporous network of polycarboxylate ligands that are crosslinked by silver(i) cations. In the intact hydrogel, ion-exchange studies are reported and it is shown that Ag~+ ions can be exchanged by copper(ii) cations without disintegration of the hydrogel. The silver(i) hydrogel shows effective antibacterial activity and potential application as burn wound dressing.