This special issue of Clinical Oncology is devoted to some of the recent significant developments in neuro-ohcology. Developments in imaging and pathology seem set to change standard management paradigms in the next few years, by allowing greater individualisation of treatment; surgical developments are improving resection in patients with glioma; radiotherapy can now deliver better dose distributions; and chemotherapy developments are gathering momentum. Particular challenges exist at the extremes of age, and treatment approaches need to be designed differently, and better, in these groups.
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