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Whole Abdominal Radiation Using Helical Tomotherapy-based Intensity-modulated Radiotherapy: A Potential for Consolidation Therapy in Adequately Treated Locally Advanced Epithelial Ovarian Cancers

机译:使用基于螺旋体层摄影术的强度调节放射疗法的整个腹部放射:在充分治疗的局部晚期上皮性卵巢癌中进行巩固疗法的潜力

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摘要

This article describes ethical, legal and professional components of the two core requirements of clinical research: informed consent and risk-benefit relationships. It deals particularly with the ethically relevant reasons, criteria, procedures and validity of (1) the informed consent process, (2) the relationship between benefits and risks, and as a requirement of its assessment: (3) standards and (quasi quantitative) criteria of benefits and risks and/or burdens of a research intervention. These requirements will be discussed with specific reference to research interventions in mentally ill patients, and particularly in those who are incompetent to consent. (4) The analysis concludes by demanding a strong adherence to the ethical rules of clinical research in order to protect participants and preserve the trust of both the patients and the public and (5) yields in a set of recommendations.
机译:本文介绍了临床研究的两个核心要求的伦理,法律和专业组成部分:知情同意和风险收益关系。它特别涉及以下方面的道德相关原因,标准,程序和有效性:(1)知情同意程序;(2)收益与风险之间的关系;以及作为其评估要求的内容:(3)标准和(准定量)研究干预措施的收益,风险和/或负担标准。将特别参考针对精神病患者(尤其是那些无能力同意的患者)的研究干预措施来讨论这些要求。 (4)分析的结尾是要求严格遵守临床研究的道德规则,以保护参与者并维护患者和公众的信任,并且(5)提出了一系列建议。

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