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Cytokines play an important role in the pathogenesis of Lymphomas . The aim of this study was to determine the diagnostic value of interleukin-6 (IL-6) levels in sera of patients with non-Hodgkin's lymphoma (NHL), and to establish its expression in neoplastic cells. The ability of NHL to produce IL-6 was examined by determining IL-6 mRNA levels. Finally, the prognostic value of serum IL-6 in NHL was estimated by taking into consideration the response to treatment and overall survival.
机译:细胞因子在淋巴瘤的发病机制中起重要作用。这项研究的目的是确定白细胞介素6(IL-6)水平在非霍奇金淋巴瘤(NHL)患者血清中的诊断价值,并确定其在肿瘤细胞中的表达。通过确定IL-6 mRNA水平来检查NHL产生IL-6的能力。最后,通过考虑对治疗的反应和总体生存率来评估血清IL-6在NHL中的预后价值。

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