Experimental inversion of optical diffraction tomography data with a nonlinear algorithm in the multiple scattering regime

摘要

Optical diffraction tomography (ODT) is a recent imaging technique that combines the experimental methods of phase microscopy and synthetic aperture with the mathematical tools of inverse scattering theory. We present here in detail how this technique can be applied to highly scattering samples with a nonlinear inversion algorithm taking into account multiple scattering to reconstruct their permittivity profile. The obtained resolutions are substantially improved compared with wide-field microscopy and ODT performed with standard linear inversion procedures.