Incidental Detection of Thoracoomphalopagus at Amniocentesis in a Twin Pregnancy

摘要

A 41-year-old, gravida 2, para 1 woman was referred for amniocentesis at 16 weeks of gestation because of advanced maternal age. Her husband was 48 years old. The couple had a 2-year-old healthy son. She had never undergone assisted reproductive technologies (ARTs). Prenatal ultrasound at 8 weeks of gestation did not detect conjoined twins (Fig. 1). At 16 weeks of gestation, prenatal ultrasound examinations before amniocentesis revealed conjoined twins with thoracoomphalopagus and separate hearts (Fig. 2). The woman refused to undergo amniocentesis and elected to terminate the pregnancy, and a 214-g female thoracoomphalopagus was delivered (Fig. 3). Postnatal cytogenetic analysis of fetal tissues revealed a karyotype of 46,XX.