A new method for long-term storage of titred microbial standard solutions suitable for microbiologic quality control activities of pharmaceutical companies

摘要

Commercially available lyophilized microbial standards are expensive and subject to reduction in cell viability due to freeze-drying stress. Here we introduce an inexpensive and straightforward method for in-house microbial standard preparation and cryoconservation that preserves constant cell titre and cell viability over 14 months. (C) 2016 Elsevier B.V. All rights reserved.