LC/MS/MS analysis of alpha-tocopherol and coenzyme Q(10) content in lyophilized royal jelly, beebread and drone homogenate

摘要

This study shows the results of application liquid chromatography-tandem mass spectrometry (LC/MS/MS) for assay of the content of alpha-tocopherol and coenzyme Q(10) in bee products of animal origin, i.e. royal jelly, beebread and drone homogenate. The biological matrix was removed using extraction with n-hexane. It was found that drone homogenate is a rich source of coenzyme Q(10). It contains only 8 +/- 1 mu g/g of alpha-tocopherol and 20 +/- 2 mu g/g of coenzyme Q(10). The contents of assayed compounds in royal jelly were 16 +/- 3 and 8 +/- 0.2 mu g/g of alpha-tocopherol and coenzyme Q(10), respectively. Beebread appeared to be the richest of alpha-tocopherol. Its level was 80 +/- 30 mu g/g, while the level of coenzyme Q(10) was only 11.5 +/- 0.3 mu g/g. Copyright (C) 2016 John Wiley & Sons, Ltd.