IMPROVED METHOD FOR LABELING OF ANTI-CEA HUMANIZED CHIMERIC ANTIBODY RCH24 WITH ~131I

Z. Yang; Y. Rang; B. Xu; Z. Yang; X. Wang

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IMPROVED METHOD FOR LABELING OF ANTI-CEA HUMANIZED CHIMERIC ANTIBODY RCH24 WITH ~131I

机译：〜131I标记抗CEA人源化嵌合抗体RCH24的改进方法

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摘要

Objective: To provide a effective radioactive agent for radioimmunoguided surgery, a improved method for ~131I labeling antibody was developed, which is of speediness, high efficiency, high specific activity and less loss of immunoreactivity.

机译：目的：为快速，高效，高比活度和免疫反应性损失的减少提供一种改良的〜131I标记抗体的方法，为放射免疫导向手术提供一种有效的放射性药物。

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《Journal of Labelled Compounds and Radiopharmaceuticals》 |2005年第0期|共1页
作者
Z. Yang; Y. Rang; B. Xu; Z. Yang; X. Wang;
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原文格式 PDF
正文语种 eng
中图分类药学;
关键词
Monoclonal Antibody; Radiolabeled; Iodine-131;

机译：单克隆抗体;放射性标记;碘131;

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专利

1. IMPROVED METHOD FOR LABELING OF ANTI-CEA HUMANIZED CHIMERIC ANTIBODY RCH24 WITH ~131I [J] . Z. Yang, Y. Rang, B. Xu, Journal of Labelled Compounds and Radiopharmaceuticals . 2005,第0期

机译：〜131I标记抗CEA人源化嵌合抗体RCH24的改进方法
2. Tumor-Specific Labeling of Pancreatic Cancer Using a Humanized Anti-CEA Antibody Conjugated to a Near-Infrared Fluorophore [J] . Lwin Thinzar M., Murakami Takashi, Miyake Kentaro, Annals of surgical oncology . 2018,第4期

机译：使用与近红外荧光团缀合的人源化抗CEA抗体的肿瘤特异性标记胰腺癌
3. A Phase I Trial Combining High-Dose 90Y-Labeled Humanized Anti-CEA Monoclonal Antibody with Doxorubicin and Peripheral Blood Stem Cell Rescue in Advanced Medullary Thyroid Cancer. [J] . Sharkey RM, Hajjar G, Yeldell D, The Journal of Nuclear Medicine . 2005,第4期

机译：结合高剂量90Y标签的人源化抗CEA单克隆抗体与阿霉素和外周血干细胞抢救的晚期甲状腺髓样癌的I期试验。
4. Fluorescent humanized anti-CEA antibody specifically labels metastatic pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model [C] . Thinzar M. Lwin, Kentaro Miyake, Takashi Murakami, Molecular-Guided Surgery: Molecules, Devices, and Applications IV . 2018

机译：荧光人源化抗CEA抗体在源自患者的原位异种移植（PDOX）小鼠模型中特异性标记转移性胰腺癌
5. Characterization of Anti-Ricin Monoclonal Antibodies and the Construction of a Chimeric Murine-Human IgG2/K Anti-Ricin Monoclonal Antibody [D] . Vendramelli, Robert Matthew 2011

机译：抗蓖麻毒蛋白单克隆抗体的表征和鼠/人IgG2 / K嵌合抗蓖麻毒蛋白单克隆抗体的构建
6. Fluorescently-labeled chimeric anti-CEA antibody improves detection and resection of human colon cancer in an orthotopic nude mouse model [O] . Cristina A. Metildi, Sharmeela Kaushal, George A. Luiken, -1

机译：荧光标记的嵌合抗CEA抗体可改善原位裸鼠模型中人结肠癌的检测和切除
7. Fluorescent humanized anti-CEA antibody specifically labels metastatic pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model [O] . Thinzar M. Lwin, Kentaro Miyake, Takashi Murakami, 2018

机译：荧光人源化抗CEA抗体特异性标记患者衍生的原位异种移植物（PDOX）小鼠模型中的转移性胰腺癌
8. Improved method for the direct labeling of antibodies with Tc-99m. [R] . Rhodes, B. A., Hawkins, E., Budd, P., 1990

机译：用Tc-99m直接标记抗体的改进方法。

IMPROVED METHOD FOR LABELING OF ANTI-CEA HUMANIZED CHIMERIC ANTIBODY RCH24 WITH ~131I

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