Preparation of ~(~(14))C_2-cis-l,2-dichloroethylene from ~(14)C_2-trichloroethylene using a cobalt porphyrin catalyst

摘要

A protocol for producing ~(14)C_2-cis-l,2-dichloroethylene (~(14)C_2-cis-DCE) from ~(14)C_2-trichloroethylene (~(14)C_2-TCE) was developed as an economical alternative to commercial, custom synthesis of ~(14)C_2-cis-DCE. The method uses 5,10,15,20-tetrakis-(4-carboxyphenyl) porphyrin cobalt(II) as a catalyst in the presence of titanium(III) citrate to convert ~(14)C_2-TCE to ~(14)C_2-cis-DCE as shown in Figure 1. A purge-and-trap technique was used to isolate ~(14)C_2-CIS-DCE to provide a methanolic stock solution of high purity (97% cis-DCE). The overall ~(14)C_2-cis-DCE yield of the process was approximately 53%.