Reductions in serum levels of LDL cholesterol, apolipoprotein B, triglycerides and lipoprotein(a) in hypercholesterolaemic patients treated with the liver-selective thyroid hormone receptor agonist eprotirome

Angelin Bo; Kristensen Jens D.; Eriksson Mats; Carlsson Bo; Klein Irwin; Olsson Anders G.; Ridgway E. Chester; Ladenson Paul W.

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Reductions in serum levels of LDL cholesterol, apolipoprotein B, triglycerides and lipoprotein(a) in hypercholesterolaemic patients treated with the liver-selective thyroid hormone receptor agonist eprotirome

机译：肝选择性甲状腺激素受体激动剂治疗的高胆固醇血症患者的血清LDL胆固醇，载脂蛋白B，甘油三酸酯和脂蛋白（a）降低

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BackgroundLiver-selective thyromimetic agents could provide a new approach for treating dyslipidaemia.

机译：背景肝脏选择性胸苷药可以提供治疗血脂异常的新方法。

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来源
《Journal of Internal Medicine》 |2015年第3期|共12页
作者
Angelin Bo; Kristensen Jens D.; Eriksson Mats; Carlsson Bo; Klein Irwin; Olsson Anders G.; Ridgway E. Chester; Ladenson Paul W.;
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正文语种 eng
中图分类内科学;
关键词
cholesterol; hypercholesterolaemia; lipoprotein; liver; thyroid;

机译：胆固醇;高胆固醇血症;脂蛋白;肝;甲状腺;

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1. Reductions in serum levels of LDL cholesterol, apolipoprotein B, triglycerides and lipoprotein(a) in hypercholesterolaemic patients treated with the liver-selective thyroid hormone receptor agonist eprotirome [J] . Angelin Bo, Kristensen Jens D., Eriksson Mats, Journal of Internal Medicine . 2015,第3期

机译：肝选择性甲状腺激素受体激动剂治疗的高胆固醇血症患者的血清LDL胆固醇，载脂蛋白B，甘油三酸酯和脂蛋白（a）降低
2. Thyroid hormone receptor agonists reduce serum cholesterol independent of the LDL receptor [J] . LinJ.Z., MartagónA.J., HsuehW.A., Endocrinology . 2012,第12期

机译：甲状腺激素受体激动剂可降低血清胆固醇，而与LDL受体无关
3. Low low-density lipoprotein (LDL), cholesterol and triglycerides plasma levels are associated with reduced risk of arterial occlusive events in chronic myeloid leukemia patients treated with ponatinib in the real-life. A Campus CML study [J] . Giovanni Caocci, Olga Mulas, Isabella Capodanno, Blood cancer journal. . 2020,第6期

机译：低密度脂蛋白（LDL），胆固醇和甘油三酯血浆水平与在现实生活中Ponatinib治疗的慢性骨髓白血病患者中动脉闭塞事件的风险降低。校园CML学习
4. The Arg282Ser missense mutation in APOA5 gene determines a reduction of triglyceride and LDL-cholesterol in children together with low serum levels of apolipoprotein A-V [O] . Laura Bertoccini, Federica Sentinelli, Michela Incani, 2017

机译：APOA5基因的Arg282Ser错义突变决定了儿童甘油三酸酯和LDL-胆固醇的降低以及载脂蛋白A-V的血清水平低
5. The Arg282Ser missense mutation in APOA5 gene determines a reduction of triglyceride and LDL-cholesterol in children, together with low serum levels of apolipoprotein A-V [O] . Bertoccini, Laura, Sentinelli, Federica, Incani, Michela, 2017

机译：APOA5基因的Arg282Ser错义突变决定了儿童甘油三酸酯和LDL-胆固醇的降低以及载脂蛋白A-V的血清水平低

Reductions in serum levels of LDL cholesterol, apolipoprotein B, triglycerides and lipoprotein(a) in hypercholesterolaemic patients treated with the liver-selective thyroid hormone receptor agonist eprotirome

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