Preparation of isotopically labeled standards of spinetoram

摘要

Spinetoram is a semi-synthetic natural product composed primarily of two major factors, spinetoram J and L. Isotopically labeled standards ( ~(13)C, ~(14)C and ~2H) of both spinetoram J and L, and their major metabolites, were prepared. These standards were used to support registration studies and metabolite identification.