PREPARATION OF N.C.A. [~18F]FLUOROPHENYLUREAS

摘要

Modifications at a phenylurea moiety is often a useful tool to improve the pharmacological properties of drugs. The introduction of a fluorine-atom is widely used to modify the pharmacologically-active site of a molecule. In this regard there is a need for devolpment of new radiolabelling methods to prepare no-carrier-added fluorine-18 labelled fluorophenyl urea moieties.