首页> 外文期刊>Journal of Inorganic Biochemistry: An Interdisciplinary Journal >Synthesis and antitumor activity of cyclopentadienyltitanium substituted polyoxotungstate [CoW11O39(CpTi)](7-) (CP=eta(5)-C5H5)
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Synthesis and antitumor activity of cyclopentadienyltitanium substituted polyoxotungstate [CoW11O39(CpTi)](7-) (CP=eta(5)-C5H5)

机译:环戊二烯基钛取代的聚氧钨酸盐[CoW11O39(CpTi)](7-)(CP = eta(5)-C5H5)的合成及抗肿瘤活性

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摘要

A novel polyoxotungstate [CoW11O39(CpTi)](7-) (Cp=eta(5)-C5H5) has been prepared. This complex exhibits the highest antitumor activity in vitro among the cyclopentadienyltitanium substituted polyoxometalates investigated and has a remarkable inhibitory action on three types of human cancer cells, SSMC-7721, HL-60 and HLC, in vivo. (C) 2002 Published by Elsevier Science Inc. [References: 9]
机译:新型的聚氧钨酸盐[CoW11O39(CpTi)](7-)(Cp = eta(5)-C5H5)已制备。该复合物在所研究的环戊二烯基钛取代的多金属氧酸盐中具有最高的体外抗肿瘤活性,并且在体内对三种类型的人类癌细胞SSMC-7721,HL-60和HLC具有显着的抑制作用。 (C)2002由Elsevier Science Inc.出版[参考文献:9]

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