Trends in the Epidemiology of Candida Bloodstream Infections in Northern Ireland between January 1984 and December 2000.

摘要

OBJECTIVE: To describe the epidemiology of Candida bloodstream infections (BSI) in Northern Ireland.METHODS: Retrospective collation of data relating to all clinically significant BSI in a university teaching hospital, which had been recorded prospectively, between 1984 and 2000.RESULTS: One hundred and forty five episodes of candidaemia occurred in 144 patients (of mean age 56.6 years). The contribution of Candida spp. towards all significant BSI increased from 2.0% to 2.5%. C. albicans was the most frequently isolated species, however, its incidence fell from 70% to 53% during the study period. The greatest increase in incidence was seen with C. glabrata which was the most common non-albicans species. Twenty-nine per cent of isolates occurred in patients from an intensive care unit and, surprisingly, a further 25.5% occurred in patients from a surgical service.CONCLUSION: There appears to be several subtle differences in the epidemiology of candidal BSI between Northern Ireland and other countries.