EFFECTS OF ITRACONAZOLE AND GEMFIBROZIL ON ARN-509 PHARMACOKINETICS (PK): COMPARISON OF IN SILICO PREDICTIONS BY PHYSIOLOGIC-BASED PK (PBPK) MODELING AND IN VIVO RESULTS.

Chien C.; Van den Bergh A.; Saad F.; Ward P.; Snoeys J.; Stieltjes H.; Jiao J.; Hellemans P.

首页> 外文期刊>Clinical Pharmacology and Therapeutics >EFFECTS OF ITRACONAZOLE AND GEMFIBROZIL ON ARN-509 PHARMACOKINETICS (PK): COMPARISON OF IN SILICO PREDICTIONS BY PHYSIOLOGIC-BASED PK (PBPK) MODELING AND IN VIVO RESULTS.

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EFFECTS OF ITRACONAZOLE AND GEMFIBROZIL ON ARN-509 PHARMACOKINETICS (PK): COMPARISON OF IN SILICO PREDICTIONS BY PHYSIOLOGIC-BASED PK (PBPK) MODELING AND IN VIVO RESULTS.

机译：依他康唑和吉非环唑对ARN-509药代动力学（PK）的影响：基于生理学的PK（PBPK）建模和体内结果的硅酮预测的比较。

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《Clinical Pharmacology and Therapeutics》 |2016年第1期|共1页
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Chien C.; Van den Bergh A.; Saad F.; Ward P.; Snoeys J.; Stieltjes H.; Jiao J.; Hellemans P.;
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正文语种 eng
中图分类药理学;
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1. EFFECTS OF ITRACONAZOLE AND GEMFIBROZIL ON ARN-509 PHARMACOKINETICS (PK): COMPARISON OF IN SILICO PREDICTIONS BY PHYSIOLOGIC-BASED PK (PBPK) MODELING AND IN VIVO RESULTS. [J] . Chien C., Van den Bergh A., Saad F., Clinical Pharmacology and Therapeutics . 2016,第Suppla1期

机译：依他康唑和吉非环唑对ARN-509药代动力学（PK）的影响：基于生理学的PK（PBPK）建模和体内结果的硅酮预测的比较。
2. EVALUATION OF PHYSIOLOGICALLY BASED PHARMACOKINETIC (PBPK) MODEL IN PREDICTING PHARMACOKINETICS (PK) OF DACOMITINIB AND METABOLITE IN HEALTHY CHINESE SUBJECTS. [J] . Liu J., Saravanakumar A., Lin J. Clinical Pharmacology and Therapeutics . 2020,第S1期

机译：基于生理基础的药代动力学（PBPK）模型在预测达科米基因和中药代谢物中的药代动力学（PK）。
3. APPLICATION OF PHYSIOLOGICALLY-BASED PHARMACOKINETIC (PBPK) MODEL IN PREDICTING PREGABALIN PHARMACOKINETICS (PK) IN PEDIATRIC POPULATIONS [J] . Liu J., Alvey C. W., Chew M. L., Clinical Pharmacology and Therapeutics . 2014,第Suppla1期

机译：基于生理的药代动力学（PBPK）模型在小儿人群中的前降巴林药代动力学（PK）预测中的应用
4. PD/PK Characterization of Drug Release From Nanoparticles Independent of Formulation: Acute Pharmacokinetics and Cardiovascular Effects of Intravenous Nifedipine [C] . Vrbanac JJ, Humphrey SJ, Buhl AE, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2009

机译：纳米颗粒的Pd / PK表征药物释放独立于制剂：静脉注射氮素的急性药代动力学和心血管作用
5. Mechanism-based pharmacokinetic/pharmacodynamic PK/PD modeling of corticosteroids and antiretrovirals. [D] . Fang, Jing. 2012

机译：皮质类固醇和抗逆转录病毒药物的基于机理的药代动力学/药效动力学PK / PD建模。
6. In vivo Pharmacokinetic and Pharmacodynamic (PK/PD) Modeling and Establishment of the PK/PD Cutoff of Florfenicol Against Pasteurella multocida in Ducks [O] . Xia Xiao, Weixuan Lan, Yaqin Zhao, 2020

机译：在体内药代动力学和药效学（PK / PD）模拟和建立叶片中Flasteurella Multocida的PK / PD截止的影响和建立
7. In vivo Pharmacokinetic and Pharmacodynamic (PK/PD) Modeling and Establishment of the PK/PD Cutoff of Florfenicol Against Pasteurella multocida in Ducks [O] . Xia Xiao, Weixuan Lan, Yaqin Zhao, 2021

机译：在体内药代动力学和药效学（PK / PD）模拟和建立叶片中Flasteurella Multocida的PK / PD截止的影响和建立
8. Chloroform: A Physiologically-based Pharmacokinetic Model Including Cytotoxicity as an Endpoint Part A: Development of the Pb-pk Model (final Report) with Cover Letter dated 011489. [R] . 1989

机译：氯仿：基于生理学的药代动力学模型，包括细胞毒性作为终点a部分：pb-pk模型的开发（最终报告），封面信函日期为011489。

EFFECTS OF ITRACONAZOLE AND GEMFIBROZIL ON ARN-509 PHARMACOKINETICS (PK): COMPARISON OF IN SILICO PREDICTIONS BY PHYSIOLOGIC-BASED PK (PBPK) MODELING AND IN VIVO RESULTS.

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