Efficient Synthesis of Benzimidazo[1,2-a]pyrimidinone Derivatives via Catalyst-Free Reactions of Baylis–Hillman Acetates, Alcohols, and Amines with 2-Aminobenzimidazole

摘要

Benzimidazo[1,2-a]pyrimidinone and its derivatives were easily prepared in good to excellent yields via tandem reactions of 2-aminobenzimidazole with Baylis–Hillman acetates, alcohols, and amines without the use of catalyst and additive in one-pot process. The method provided an efficient and facile route to the title fused heterocyclic compounds with different functional groups.