A Simple, Efficient, One-Pot Three-Component Domino Synthesis of Hantzsch Pyridines under Solvent-Free Condition

摘要

In this article, efficient and simple preparation of Hantzsch pyridine derivatives by reaction of various aldehydes and beta-dicarbonyls in the presence of ammonium chlorate under solvent-free condition at 80 degrees C is reported. The advantages of this system are the one-step procedure, high yields of the products, and the ability to carry out large-scale reactions.