Synthesis of thiazolo[3,2-d][1,2,4] triazines through palladium-catalyzed heteroannulation of acetylenic compounds

摘要

The reaction of 6-methyl-5-(prop-2-ynylthio)-5,6-dihydro-1,2,4-triazin-3(4H)-one 1 with various iodobenzenes 2 in the presence of palladium catalyst leads to the formation of substituted triazolotriazines.