Eco-friendly synthesis of quinoxaline derivatives by grinding under solvent-free conditions

摘要

An efficient and facile synthesis of quinoxaline derivatives in excellent isolated yields by the condensation of 1,2-diamines and 1,2-diketones on grinding under solvent-free conditions at ambient temperature has been developed. The important features of this method are that it is reasonably fast, very clean, high yielding, simple workup, and environmentally benign.