New synthesis, X-ray structural determination, conformational analysis and anomeric effect study of 3,7-di(3-nitrophenyl)-1,5-dioxa-3,7-diazacyclooctane

摘要

3,7-Di(3-nitrophenyl)-1,5-dioxa-3,7-diazacyclooctane was prepared from 3-nitroaniline and formaldehyde in acetonitrile. Conformational behavior of ring inversion of the molecule was studied so it prefers a crown conformation. The evaluated Delta G(#) was approximately 58.0 +/- 1.0 kJ/mole. The X-ray structure determination of the compound shows a crown conformation, in line with two-anomeric effect in N-C-O moiety.