Synthesis and crystal structure of 5-pyrazol-4,5-dihydropyrazoles derivatives

摘要

A series of 1-acetyl(or phenyl)-3-aryl-5-(1-phenyt-3-methyl-5-aryloxyl-pyrazol)-4,5-dihydropyrazole derivatives have been efficiently synthesized under refluxing in glacial acetic acid with two kinds of hydrazines and five kinds of chalcones of 1-phenyl-methyl-5-phenoxyl-pyrazol-4-aldehyde. The structures were confirmed on the basis of H-1 NMR, IR, MS and element analysis, and the crystal structure of the compound 4c was determined by single crystal X-ray diffraction. The compound 4c belongs to monoclinic system with space group P2(1), a = 11.8779(3) rum, b = 12.0901(2) rum, c = 17.7004(4) nm, alpha= 90 degrees, beta=100.05(10)degrees, gamma = 90 degrees, Formula weight: 549.46, Triclinic V =2502.89(9) nm(3), D-c =1.458 Mg/m(3), Z = 4, F (000) = 1128.