Targeted-bisulfite sequence analysis of the methylation of CpG islands in genes encoding PNPLA3, SAMM50, and PARVB of patients with non-alcoholic fatty liver disease

Kitamoto Takuya; Kitamoto Aya; Ogawa Yuji; Honda Yasushi; Imajo Kento; Saito Satoru; Yoneda Masato; Nakamura Takahiro; Nakajima Atsushi; Hotta Kikuko

首页> 外文期刊>Journal of Hepatology: The Journal of the European Association for the Study of the Liver >Targeted-bisulfite sequence analysis of the methylation of CpG islands in genes encoding PNPLA3, SAMM50, and PARVB of patients with non-alcoholic fatty liver disease

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Targeted-bisulfite sequence analysis of the methylation of CpG islands in genes encoding PNPLA3, SAMM50, and PARVB of patients with non-alcoholic fatty liver disease

机译：非酒精性脂肪肝患者编码PNPLA3，SAMM50和PARVB的基因中CpG岛甲基化的靶向亚硫酸氢盐序列分析

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Background & Aims: The pathogenesis of non-alcoholic fatty liver disease (NAFLD) is affected by epigenetic factors as well as by genetic variation.

机译：背景与目的：非酒精性脂肪性肝病（NAFLD）的发病机理受表观遗传因素以及遗传变异的影响。

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《Journal of Hepatology: The Journal of the European Association for the Study of the Liver》 |2015年第2期|共9页
作者
Kitamoto Takuya; Kitamoto Aya; Ogawa Yuji; Honda Yasushi; Imajo Kento; Saito Satoru; Yoneda Masato; Nakamura Takahiro; Nakajima Atsushi; Hotta Kikuko;
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正文语种 eng
中图分类消化系及腹部疾病;
关键词
Non-alcoholic fatty liver disease; DNA methylation; Next-generation sequencing; Fibrosis; PNPLA3; SAMM50; PARVB;

机译：非酒精性脂肪肝;DNA甲基化;下一代测序;纤维化;PNPLA3;SAMM50;PARVB;

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专利

1. 宫颈癌组织中FHIT基因5'端CpG岛甲基化及其与基因失活的关系 [J] . 史惠蓉, 吴庆华, 索振河, 癌症（英文版） . 2005,第001期
2. Targeted-bisulfite sequence analysis of the methylation of CpG islands in genes encoding PNPLA3, SAMM50, and PARVB of patients with non-alcoholic fatty liver disease [J] . Kitamoto Takuya, Kitamoto Aya, Ogawa Yuji, Journal of Hepatology: The Journal of the European Association for the Study of the Liver . 2015,第2期

机译：非酒精性脂肪肝患者编码PNPLA3，SAMM50和PARVB的基因中CpG岛甲基化的靶向亚硫酸氢盐序列分析
3. Genetic Polymorphisms of PNPLA3 and SAMM50 Are Associated with Nonalcoholic Fatty Liver Disease in a Korean Population [J] . Goh Eun Chung, Young Lee, Jeong Yoon Yim, Gut and Liver . 2018,第3期

机译：PNPLA3和SAMM50的遗传多态性与韩国人群的非酒精性脂肪肝相关。
4. Targeted next-generation sequencing and fine linkage disequilibrium mapping reveals association of PNPLA3 and PARVB with the severity of nonalcoholic fatty liver disease [J] . KitamotoT., KitamotoA., YonedaM., Journal of human genetics . 2014,第5期

机译：有针对性的下一代测序和精细连锁不平衡作图揭示了PNPLA3和PARVB与非酒精性脂肪肝疾病的严重程度相关
5. Liver stiffness measurement using transient elastography in patients with non-alcoholic fatty liver (NAFLD) and non-alcoholic steatohepatitis (NASH) [C] . Veronique Miette, Celine Fournier, Linda Adara, IEEE Ultrasonics Symposium . 2007

机译：利用非酒精脂肪肝（NAFLD）和非酒精脱脂肝炎（NASH）患者使用瞬态弹性术（NASH）的肝硬化测量
6. Metabolic syndrome in non-alcoholic fatty liver disease: A comparison between simple steatosis and non-alcoholic steatohepatitis [D] . Avand, Ghazal 2006

机译：非酒精性脂肪肝疾病的代谢综合征：单纯性脂肪变性和非酒精性脂肪性肝炎的比较
7. Genetic Polymorphisms of PNPLA3 and SAMM50 Are Associated with Nonalcoholic Fatty Liver Disease in a Korean Population [O] . Goh Eun Chung, Young Lee, Jeong Yoon Yim, 2018

机译：PNPLA3和SAMM50的遗传多态性与韩国人群的非酒精性脂肪肝相关。
8. Targeted-bisulfite sequence analysis of the methylation of CpG islands in genes encoding PNPLA3, SAMM50, and PARVB of patients with non-alcoholic fatty liver disease [O] . Takuya Kitamoto, Aya Kitamoto, Yuji Ogawa, 2015

机译：靶向二硫酸氢盐序列分析，对非酒精脂肪肝病患者PNPLA3，SAMM50和PARVB的基因中CpG岛的甲基化

Targeted-bisulfite sequence analysis of the methylation of CpG islands in genes encoding PNPLA3, SAMM50, and PARVB of patients with non-alcoholic fatty liver disease

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