Effect of proton-pump inhibitors on the risk of lower gastrointestinal bleeding associated with NSAIDs, aspirin, clopidogrel, and warfarin

Nagata Naoyoshi; Niikura Ryota; Aoki Tomonori; Sakurai Toshiyuki; Moriyasu Shiori; Shimbo Takuro; Sekine Katsunori; Okubo Hidetaka; Watanabe Kazuhiro; Yokoi Chizu; Yanase Mikio; Akiyama Junichi; Uemura Naomi

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Effect of proton-pump inhibitors on the risk of lower gastrointestinal bleeding associated with NSAIDs, aspirin, clopidogrel, and warfarin

机译：质子泵抑制剂对与NSAID，阿司匹林，氯吡格雷和华法林相关的下消化道出血风险的影响

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Background We investigated the effects of proton-pump inhibitors (PPIs) on lower gastrointestinal bleeding (LGIB) and of their interactions with nonsteroidal anti-inflammatory drugs (NSAIDs), low-dose aspirin, clopidogrel, and warfarin on LGIB risk.

机译：背景我们研究了质子泵抑制剂（PPI）对下消化道出血（LGIB）的影响以及它们与非甾体抗炎药（NSAIDs），低剂量阿司匹林，氯吡格雷和华法林对LGIB风险的影响。

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《Journal of gastroenterology》 |2015年第11期|共8页
作者
Nagata Naoyoshi; Niikura Ryota; Aoki Tomonori; Sakurai Toshiyuki; Moriyasu Shiori; Shimbo Takuro; Sekine Katsunori; Okubo Hidetaka; Watanabe Kazuhiro; Yokoi Chizu; Yanase Mikio; Akiyama Junichi; Uemura Naomi;
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正文语种 eng
中图分类消化系及腹部疾病;
关键词
Lower gastrointestinal tract hemorrhage; Antisecretory drugs; Drug-drug interaction;

机译：下消化道出血;抗分泌药物;药物相互作用;

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专利

1. Effect of proton-pump inhibitors on the risk of lower gastrointestinal bleeding associated with NSAIDs, aspirin, clopidogrel, and warfarin [J] . Nagata Naoyoshi, Niikura Ryota, Aoki Tomonori, Journal of gastroenterology . 2015,第11期

机译：质子泵抑制剂对与NSAID，阿司匹林，氯吡格雷和华法林相关的下消化道出血风险的影响
2. Cardiovascular and gastrointestinal events of three antiplatelet therapies: clopidogrel, clopidogrel plus proton-pump inhibitors, and aspirin plus proton-pump inhibitors in patients with previous gastrointestinal bleeding [J] . Yi-Wen Tsai, Yu-Wen Wen, Weng-Foung Huang, Journal of Gastroenterology . 2011,第1期

机译：先前有胃肠道出血的患者的三种抗血小板疗法的心血管和胃肠道事件：氯吡格雷，氯吡格雷加质子泵抑制剂以及阿司匹林加质子泵抑制剂
3. Aspirin and Proton-Pump Inhibitors Compared to Clopidogrel in Patients with History of Gastrointestinal Bleeding and Aspirin Consumption [J] . Advanced Science Letters . 2017,第7期

机译：阿司匹林和质子泵抑制剂与胃肠道出血历史和阿司匹林消费患者的氯吡格雷相比
4. Animal Model for Evaluating Gastric Bleeding and Ulcerogenic Response Induced by Aspirin plus Clopidogrel [C] . Chitose Izuhara, Shinichi Takayama, Misaki Itayama, International Symposium on Cell/Tissue Injury and Cytoprotection/Organoprotection: Focus on GI Tract . 2012

机译：Aspirin Plus Clopidogrel评估胃损出和溃疡性反应的动物模型
5. Prostate cancer risk and inflammation: Association with aspirin and other NSAID use & selected inflammation pathway-related gene polymorphisms. [D] . Salinas, Claudia A. 2009

机译：前列腺癌的风险和炎症：与阿司匹林和其他NSAID的使用以及选定的炎症途径相关的基因多态性相关。
6. Prognosis of concomitant users of clopidogrel and proton-pump inhibitors in a high-risk population for upper gastrointestinal bleeding [O] . Qing Wang, Rickard Ljung, Jesper Lagergren, 2014

机译：高危人群上消化道出血并发氯吡格雷和质子泵抑制剂同时使用的预后
7. Combined effect of proton-pump inhibitors and other drugs with regard to lower gastrointestinal tract bleeding with special reference to low-dose aspirin [O] . Tomoyuki Kawada 2015

机译：质子泵抑制剂和其他药物对低剂量阿司匹林的较低胃肠道出血的综合作用

Effect of proton-pump inhibitors on the risk of lower gastrointestinal bleeding associated with NSAIDs, aspirin, clopidogrel, and warfarin

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