Obesity outcomes in children with a history of failure to thrive

摘要

Background: There are numerous outcome studies on the neurodevel-opmental and growth sequelae of children with failure to thrive (FTT). Most research demonstrates adverse outcomes in neurodevelopment and behavior. However, the results on long-term growth are discrepant. The majority of studies demonstrate that infants with FTT remain small throughout life, although meta-analyses suggest that growth parameters may normalize over time. There are no reports on the long-term outcome of obesity in this population. This finding would have important implications for the approach and management of FTT. If clinicians are too aggressive in nutritional repletion, this may lead to overcorrection and obesity; but inadequate intervention could lead to poor developmental outcomes.