Enzymatic syntheses of 6-(4H-selenolo(3,2-b)pyrrolyl)-L-alanine, 4-(6H-selenolo(2,3-b)pyrrolyl)-L-alanine, and 6-(4H-furo(3,2-b)pyrrolyl-L-alanine.

摘要

6-(4H-Selenolo[3,2-b]pyrrolyl)-L-alanine 1, 4-(6H-selenolo[2,3-b]pyrrolyl)-L-alanine 2, and 6-(4H-furo[3,2-b]pyrrolyl)-L-alanine 3 have been synthesized via reactions of selenolo[3,2-b]pyrrole, selenolo[2,3-b]pyrrole, and furo[3,2-b]pyrrole, respectively, with L-serine. The reactions are catalyzed by Salmonella typhimurium tryptophan synthase.