Three-fold polyfluoroalkylated amines and isocyanates based on tris(hydroxymethyl)aminomethane (TRIS)

摘要

Three-fold polyfluoroalkylated amines were prepared from tris(hydroxymethyl)aminomethane (TRIS) in five steps including perfluoroalkyl iodide addition to the corresponding allyl derivative,reduction of C-I bond and deprotection of the amino group.They can be easily converted to the corresponding isocyanates.