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Mucormycosis (zygomycosis) of renal allograft

机译:肾移植的毛霉菌病(合子菌病)

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Fungal infection is relatively common among renal transplant recipients from developing countries. Mucormycosis, also known as zygomycosis, is one of the most serious fungal infections in these patients. The most common of presentation is rhino-cerebral. Isolated involvement of a renal allograft is very rare. A thorough search of literature and our medical records yielded a total of 24 cases with mucormycosis of the transplanted kidney. There was an association with cytomegalovirus (CMV) infection and anti-rejection treatment in these patients and most of these transplants were performed in the developing countries from unrelated donors. The outcome was very poor with an early mortality in 13 (54.5) patients. Renal allograft mucormycosis is a relatively rare and potentially fatal complication following renal transplantation. Early diagnosis, graft nephrectomy and appropriate antifungal therapy may result in an improved prognosis for these patients.
机译:真菌感染在发展中国家的肾移植受者中相对普遍。毛霉菌病,也称为合子菌病,是这些患者中最严重的真菌感染之一。最常见的表现是犀牛。肾脏同种异体移植受累很少。全面检索文献和我们的病历后,总共有24例移植肾的毛霉菌病。这些患者与巨细胞病毒(CMV)感染和抗排斥治疗有关,这些移植中的大多数是在发展中国家由无关的捐助者进行的。结果非常差,有13(54.5)位患者的早期死亡。肾同种异体移植肾真菌病是一种相对罕见的肾移植术后并发症。早期诊断,移植肾切除术和适当的抗真菌治疗可能会改善这些患者的预后。

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