Changes of Functional and Biochemical Blood Parameters in Wistar Rats and in Spontaneously Hypertensive Rats of the SHR Line during Short-Term and Long Tredmill Running

摘要

Effects were studied of single(40 min)orrepeated exercise load(tredmill running,14 m/min,30 min)on the physiological and biochemical blood parameters characterizing the organism energetic and metabolic processes in complex experiments on male Wistar rats,on spontaneously hypertensive rats of the SHR line,and their normotensive control WKY.The mixed blood was used for determination of hematocrit,red blood cell count,hemoglobin concentration,level of 2,3-diphosphoglycerate(2,3-DPG)in red blood cells,erythrocyte acetylcholinesterase(AChE)activity,glucose,cholesterol,and triglyceride concentration,as well as plasma corticosterone level.To assess the erythrocyte population characteristics,the acidity erythrogram was determined.The weights of adrenal glands and spleen were evaluated.The single running induced a typical stress-response.After the repeated exercise load(the 7-14-day running),Wistar and WKY rats were well adopted to the load,unlike the SHR line rats that were practically not adapted to the repeated tredmill running.