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Spatulated end-to-end bile duct reconstruction in orthotopic liver transplantation.

机译:原位肝移植中端尾端胆管重建术。

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摘要

Biliary complications continue to be a major source of morbidity following orthotopic liver transplantation. The aim of this study was to analyze the incidence and management of biliary complications related to the technique of bile duct reconstruction. The patients were stratified into two groups: group I (n = 39) had bile duct reconstruction performed by an end-to-end single interrupted suture choledochocholedochostomy (EE-CDCD) and group II (n = 38) had a spatulated end-to-end CDCD (spEE-CDCD) reconstruction; both groups had an intraductal stent. The groups were similar in age, gender, liver transplant indications and Pugh score. Ten biliary complications (26%), including five bile leaks (13%) and five biliary strictures (13%), were observed in the EE-CDCD group, while one biliary stricture (2.6%) occurred in the spEE-CDCD group (p < 0.05). Subsequent imaging studies and endoscopic retrograde cholangiopancreatography were performed less often in patients undergoing spEE-CDCD reconstruction (p < 0.05). The technique of a spatulated end-to-end bile duct reconstruction provides a significant improvement in lowering biliary complication rates in liver transplant patients. Despite the modest number of cases in this study this technique shows promise and has become the technique of choice in our institution.
机译:胆道并发症仍然是原位肝移植术后发病的主要来源。这项研究的目的是分析与胆管重建技术有关的胆道并发症的发生和处理。将患者分为两组:第一组(n = 39)通过端到端单次间断缝合胆总管吻合术(EE-CDCD)进行胆管重建,第二组(n = 38)从头到尾呈片状末端CDCD(spEE-CDCD)重建;两组均具有导管内支架。各组的年龄,性别,肝移植适应症和Pugh评分相似。 EE-CDCD组观察到10例胆道并发症(26%),包括5例胆漏(13%)和5例胆道狭窄(13%),而spEE-CDCD组发生1例胆道狭窄(2.6%)( p <0.05)。在进行spEE-CDCD重建的患者中,进行随后的影像学研究和内镜逆行胰胆管造影的频率较低(p <0.05)。尾端端到端胆管重建术的技术在降低肝移植患者的胆道并发症发生率方面提供了显着改善。尽管本研究中的病例数很少,但该技术显示出了希望,并已成为我们机构的首选技术。

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