Synthesis and anti-inflammatory activity of some selected aminothiophene analogs.

Khan KM; Nullah Z; Lodhi MA; Jalil S; Choudhary MI; Atta Ur Rahman

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Synthesis and anti-inflammatory activity of some selected aminothiophene analogs.

机译：一些选定的氨基噻吩类似物的合成和抗炎活性。

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摘要

Some 2-aminothiophene analogs 1-6 were synthesized and characterized. Among the tested compounds, compound 1 (IC50 121.47 microM) exhibited highest while the compound 5 showed least anti-inflammatory potential (IC50 422 microM).

机译：合成并表征了一些2-氨基噻吩类似物1-6。在测试的化合物中，化合物1（IC50 121.47 microM）表现最高，而化合物5则显示出最小的抗炎潜力（IC50 422 microM）。

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《Journal of enzyme inhibition and medicinal chemistry.》 |2006年第2期|共5页
作者
Khan KM; Nullah Z; Lodhi MA; Jalil S; Choudhary MI; Atta Ur Rahman;
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正文语种 eng
中图分类酶;
关键词
analogs; Synthesis; Inhibitory Concentration 50; 半数抑制浓度;

机译：analogs;Synthesis;Inhibitory Concentration 50;半数抑制浓度;

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1. Synthesis and anti-inflammatory activity of some selected aminothiophene analogs. [J] . Khan KM, Nullah Z, Lodhi MA, Journal of enzyme inhibition and medicinal chemistry. . 2006,第2期

机译：一些选定的氨基噻吩类似物的合成和抗炎活性。
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3. Synthesis and anti-inflammatory activities of N-benzoylamino-1,2,3,6-tetrahydropyridine analogs. [J] . Mochona B, Wilson T, Redda K Drugs under Experimental and Clinical Research . 2003,第4期

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6. Chemical synthesis of echistatin a potent inhibitor of platelet aggregation from Echis carinatus: synthesis and biological activity of selected analogs. [O] . V M Garsky, P K Lumma, R M Freidinger, 1989

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7. Chemical synthesis of echistatin, a potent inhibitor of platelet aggregation from Echis carinatus: synthesis and biological activity of selected analogs. [O] . Garsky, V M, Lumma, P K, Freidinger, R M, 1989

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8. Synthesis, Hydrolytic Refractivity and Initial Bioevaluation of (R)-Etomidate Analogs. Part 1. Synthesis and Hydrolytic Refractivity of (R)-Etomidate Analogs [R] . Benecke, H. P., Harsh, S. S., King, J. W. 1987

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Synthesis and anti-inflammatory activity of some selected aminothiophene analogs.

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