Synthesis and preliminary antiproliferative evaluation of 1,3,9-triazacyclopenta(b)fluorene derivatives.

Desforges G; Picot L; Montagne C; Thiery V; Besson T; Joseph B

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Synthesis and preliminary antiproliferative evaluation of 1,3,9-triazacyclopenta(b)fluorene derivatives.

机译：1,3,9-三氮杂环戊（b）芴衍生物的合成和初步抗增殖评价。

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Novel 1,3,9-triazacyclopenta[b]fluorene-4,10-diones and 1,3,9-triazacyclopenta[b]fluorene, analogue of ellipticine, were synthesised, and evaluated in vitro for their antiproliferative activity on various breast cancer cell lines.

机译：合成了玫瑰树碱类似物新型的1,3,9-三氮杂环戊[b]芴和1,3,9-三氮杂环戊[b]芴，并在体外评估了其对多种乳腺癌的抗增殖活性细胞系。

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《Journal of enzyme inhibition and medicinal chemistry.》 |2005年第6期|共6页
作者
Desforges G; Picot L; Montagne C; Thiery V; Besson T; Joseph B;
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正文语种 eng
中图分类酶;
关键词
fluorene; Synthesis; derivatives; Evaluation;

机译：芴;合成;衍生物;评价;

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Synthesis and preliminary antiproliferative evaluation of 1,3,9-triazacyclopenta(b)fluorene derivatives.

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