Endotension is influenced by aneurysm volume: experimental findings.

摘要

PURPOSE: To investigate in an in vitro model whether and to what extent pressure is influenced by aneurysm size. METHODS: Latex aneurysms of 3 different volumes (24, 30, and 81 mL) were inserted into an in vitro circulation model. The systemic mean pressure (SP(mean)) was varied from 50 to 120 mmHg. The aneurysms were excluded using a woven polyethylene graft. Aneurysm sac mean pressure (ASP(mean)) was measured. RESULTS: In the in vitro model, endovascular aneurysm repair created a closed chamber without endoleak but showed a relevant aneurysm sac pressure. At an SP(mean) of 80 mmHg, the ASP(mean) was 42.0+/-0.6 mmHg in the 24-mL aneurysm, 40.5+/-0.5 mmHg in the 30-mL model, and 19.3+/-0.5 mmHg in the 81-mL aneurysm (p<0.05). The ASP(mean) rose with increasing SP(mean) and was inversely dependent on the aneurysm volume. CONCLUSIONS: This in vitro model demonstrated that the sac mean pressure correlated to the systemic pressure and that a greater aneurysm volume reduced aneurysm sac pressure. These datahighlight the need for further studies regarding endotension.