Detection and elimination of interference by the heterophilic antibody in antibody microarray-based immunoassay.

摘要

Antibody microarray-based multiplex immunoassays can be applied in the early and differential diagnosis, staging, and prognosis of disease (1). In addition to the technical challenges that are unique to microarrays, this approach also faces the same problems as other immunoassays, such as interference by heterophilic antibodies, when it is used in clinical applications.