Comparison of capillary electrophoresis and high performance liquid chromatography for detection and quantification of hemoglobin New York

摘要

Background: Hemoglobin (Hb) New York [beta 113 (G15) Val -> Glu, GTG -> GAG], also known as Hb Kaohsiung, is one of the most common Hb variants in South China. Currently, most used screening methods for hemoglobinopathies in South China are high performance liquid chromatography (HPLC) and capillary electrophoresis (CE). However, there is no study comparing the performance of CE and HPLC in the detection of Hb New York.