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Practice-oriented quality specifications for therapeutic drug monitoring.

机译:以实践为导向的质量指标,用于治疗药物监测。

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摘要

Allele frequencies and forensically relevant population statistics of 16 STR loci, including the new European Standard Set (ESS) loci, were estimated from 668 unrelated individuals of Caucasian appearance living in different parts of Switzerland. The samples were amplified with a combination of the following three kits: AmpFlSTR? NGM SElect?, PowerPlex? ESI17 and PowerPlex? ESX 17. All loci were highly polymorphic and no significant departure from Hardy-Weinberg equilibrium and linkage equilibrium was detected after correction for sampling.
机译:根据居住在瑞士不同地区的668名白种人无关个体估计了16个STR基因座的等位基因频率和法医相关人群统计数据,包括新的欧洲标准集(ESS)基因座。用以下三种试剂盒的组合扩增样品:AmpFlSTR? NGM SElect?,PowerPlex? ESI17和PowerPlex? ESX 17.所有位点均为高度多态性,校正采样后未发现明显偏离Hardy-Weinberg平衡和连锁平衡的情况。

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