Evaluation of a next generation direct whole blood enzymatic assay for hemoglobin A(1c) on the ARCHITECT c8000 chemistry system

Teodoro-Morrison Tracy; Janssen Marcel J. W.; Mols Jasper; Hendrickx Ben H. E.; Velmans Mathieu H.; Lotz Johannes; Lackner Karl; Lennartz Lieselotte; Armbruster David; Maine Gregory; Yip Paul M.

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Evaluation of a next generation direct whole blood enzymatic assay for hemoglobin A(1c) on the ARCHITECT c8000 chemistry system

机译：在ARCHITECT c8000化学系统上评估血红蛋白A（1c）的下一代直接全血酶法

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Background: The utility of HbA(1c) for the diagnosis of type 2 diabetes requires an accurate, precise and robust test measurement system. Currently, immunoassay and HPLC are the most popular methods for HbA(1c) quantification, noting however the limitations associated with some platforms, such as imprecision or interference from common hemoglobin variants. Abbott Diagnostics has introduced a fully automated direct enzymatic method for the quantification of HbA(1c) from whole blood on the ARCHITECT chemistry system.

机译：背景：HbA（1c）用于诊断2型糖尿病的实用性需要一个准确，精确和强大的测试测量系统。目前，免疫分析和HPLC是HbA（1c）定量的最流行方法，但是要注意与某些平台相关的局限性，例如不精确或常见血红蛋白变异体的干扰。雅培诊断技术公司推出了一种全自动直接酶法，用于在ARCHITECT化学系统上从全血中定量HbA（1c）。

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《Clinical chemistry and laboratory medicine: CCLM》 |2015年第1期|共8页
作者
Teodoro-Morrison Tracy; Janssen Marcel J. W.; Mols Jasper; Hendrickx Ben H. E.; Velmans Mathieu H.; Lotz Johannes; Lackner Karl; Lennartz Lieselotte; Armbruster David; Maine Gregory; Yip Paul M.;
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正文语种 eng
中图分类诊断学;
关键词
biological variation; diabetes; enzymatic assay; HbA(1c); method evaluation;

机译：生物学变异;糖尿病;酶法;HbA（1c）;方法评价;

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1. Evaluation of a next generation direct whole blood enzymatic assay for hemoglobin A(1c) on the ARCHITECT c8000 chemistry system [J] . Teodoro-Morrison Tracy, Janssen Marcel J. W., Mols Jasper, Clinical chemistry and laboratory medicine: CCLM . 2015,第1期

机译：在ARCHITECT c8000化学系统上评估血红蛋白A（1c）的下一代直接全血酶法
2. More on the accuracy of the Architect enzymatic assay for hemoglobin A(1c) and its traceability to the IFCC reference system [J] . Szoke Dominika, Carnevale Assunta, Pasqualetti Sara, Clinical chemistry and laboratory medicine: CCLM . 2016,第3期

机译：关于血红蛋白A（1c）的Architect酶促测定的准确性及其对IFCC参考系统的可追溯性的更多信息
3. A next generation enzymatic magnesium assay on the Abbott ARCHITECT chemistry system meets performance goals based on biological variation [J] . BaileyD., MartensP., MahW., Clinical Biochemistry . 2014,第1a2期

机译：雅培ARCHITECT化学系统上的下一代酶促镁测定满足基于生物学差异的性能目标
4. High sequence coverage by in-capillary proteolytic digest: identification and/or sequencing of hemoglobins directly from blood samples [C] . G. Pohlentz, S. Henning, M. Mormann, ASMS Conference on Mass Spectrometry and Allied Topics . 2006

机译：毛细血管内蛋白水解消化的高序列覆盖：直接从血液样品鉴定和/或血红蛋白排序
5. HEMATOLOGICAL CHANGES IN RESPONSE TO EXPOSURE TO MODERATE ALTITUDES (HEMOGLOBIN, RED BLOOD CELLS, SYSTEMIC BLOOD PRESSURE) [D] . BERRY, MICHAEL JOSEPH. 1983

机译：对中度海拔暴露的血液学变化（血红蛋白，红色血液细胞，系统性血液压力）
6. Age- and Gender-Specific Reference Intervals for Fasting Blood Glucose and Lipid Levels in School Children Measured With Abbott Architect c8000 Chemistry Analyzer [O] . Waleed Tamimi, Esam Albanyan, Yasmin Altwaijri, 2012

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Evaluation of a next generation direct whole blood enzymatic assay for hemoglobin A(1c) on the ARCHITECT c8000 chemistry system

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