TNF inhibitors directly target Th17 cells via attenuation of autonomous TNF/TNFR2 signalling in psoriasis

Shiga Takeo; Sato Kenji; Kataoka Sayo; Sano Shigetoshi

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TNF inhibitors directly target Th17 cells via attenuation of autonomous TNF/TNFR2 signalling in psoriasis

机译：TNF抑制剂通过抑制牛皮癣中的自主TNF / TNFR2信号转导直接靶向Th17细胞

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来源
《Journal of dermatological science》 |2015年第1期|共3页
作者
Shiga Takeo; Sato Kenji; Kataoka Sayo; Sano Shigetoshi;
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正文语种 eng
中图分类皮肤病学与性病学;
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1. TNF inhibitors directly target Th17 cells via attenuation of autonomous TNF/TNFR2 signalling in psoriasis [J] . Shiga Takeo, Sato Kenji, Kataoka Sayo, Journal of dermatological science . 2015,第1期

机译：TNF抑制剂通过抑制牛皮癣中的自主TNF / TNFR2信号转导直接靶向Th17细胞
2. TNF-alpha-stimulated gene 6 protein secreted by bone marrow mesenchymal stem cells attenuates intervertebral disc degeneration by inhibiting the Toll-like receptor 2/nuclear factor-kappa B signalling pathway [J] . Yang H., Tian W., Wang S., British journal of anaesthesia . 2019,第3期

机译：由骨髓间充质干细胞分泌的TNF-α刺激的基因6蛋白通过抑制Toll样受体2 /核因子-Kappa发信号通路来衰减椎间盘变性
3. Propofol attenuates TNF-α-induced MMP-9 expression in human cerebral microvascular endothelial cells by inhibiting Ca2+/CAMK Ⅱ/ERK/NF-κB signaling pathway [J] . Xiao-wei Ding, Xia Sun, Xue-fang Shen, 中国药理学报：英文版 . 2019,第010期

机译：丙泊酚通过抑制Ca2 + /CAMKⅡ/ ERK /NF-κB信号通路减弱TNF-α诱导的人脑微血管内皮细胞MMP-9表达
4. Measurement of Fc-Mediated ADCC and CDC Activity of Anti-TNFα and Anti-VEGF Therapeutic Antibodies Using Reporter-Based Bioassays and Engineered TNFα+ and VEGF+ Target Cells [C] . Hetal Marble, Denise Garvin, Jamison Grailer, Protein Engineering Summit. . 2018

机译：使用基于报道的生物测定和工程化TNFα+和VEGF +靶细胞测量抗TNFα和抗VEGF治疗抗体的FC介导的ADCC和CDC活性的测量
5. Effects of TNFAIP8 knockdown on EGFR and IGF-1R signaling and cytotoxicities of targeted drugs in non-small cell lung cancer cells [D] . Day, Timothy Francis 2015

机译：TNFAIP8组合对非小细胞肺癌细胞EGFR和IGF-1R信号传导及靶向药物的细胞毒性的影响
6. Propofol attenuated TNF-α-modulated occludin expression by inhibiting Hif-1α/ VEGF/ VEGFR-2/ ERK signaling pathway in hCMEC/D3 cells [O] . Yue Zhang, Xiaowei Ding, Changhong Miao, 2019

机译：丙泊酚通过抑制hCMEC / D3细胞中的Hif-1α/ VEGF / VEGFR-2 / ERK信号通路来减弱TNF-α调节的闭合蛋白表达
7. Propofol attenuated the effect of TNF-α on occludin expression by inhibiting HIF-1α/VEGF/VEGFR-2/ERK signaling pathway in hCMEC/D3 cells [O] . Yue Zhang, Xiaowei Ding, Changhong Miao, 2019

机译：异丙酚通过抑制HFMEC / D3细胞中的HIF-1α/ VEGF / VEGFR-2 / ERK信号通路抑制TNF-α对闭塞蛋白表达的影响

TNF inhibitors directly target Th17 cells via attenuation of autonomous TNF/TNFR2 signalling in psoriasis

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