Effectiveness of localized ultrasound-targeted microbubble destruction with doxorubicin liposomes in H22 mouse hepatocellular carcinoma model

Zhu Fangyu; Jiang Yong; Luo Fang; Li Pan

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Effectiveness of localized ultrasound-targeted microbubble destruction with doxorubicin liposomes in H22 mouse hepatocellular carcinoma model

机译：阿霉素脂质体局部超声靶向微泡破坏在H22小鼠肝细胞癌模型中的有效性

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Objective: In order to increase local drug concentration and reduce systemic side effects of liver cancer chemotherapy, it is desirable to develop novel non-invasive technologies for drug targeting, such as ultrasound-targeted microbubble destruction (UTMD).

机译：目的：为了增加局部药物浓度并减少肝癌化疗的全身副作用，期望开发新的非侵入性药物靶向技术，例如超声靶向微泡破坏（UTMD）。

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《Journal of drug targeting》 |2015年第10期|共12页
作者
Zhu Fangyu; Jiang Yong; Luo Fang; Li Pan;
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正文语种 eng
中图分类药学;
关键词
Acoustic cavitation; doxorubicin liposome; HCC therapy; liver tumor; ultrasound-targeted microbubble destruction;

机译：声空化阿霉素脂质体HCC治疗肝肿瘤超声靶向微泡破坏;

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专利

1. Effectiveness of localized ultrasound-targeted microbubble destruction with doxorubicin liposomes in H22 mouse hepatocellular carcinoma model [J] . Zhu Fangyu, Jiang Yong, Luo Fang, Journal of drug targeting . 2015,第1a10期

机译：阿霉素脂质体局部超声靶向微泡破坏在H22小鼠肝细胞癌模型中的有效性
2. Local Tumor Ischemia-Reperfusion Mediated By Ultrasound-Targeted Microbubble Destruction Enhances The Anti-Tumor Efficacy Of Doxorubicin Chemotherapy [J] . Manxiang Wu, Zhuqing Song, Shiyu Zhang, Cancer Management and Research . 2019,第4期

机译：通过超声靶向微泡破碎介导的局部肿瘤缺血再灌注增强了多柔比蛋白化疗的抗肿瘤效果
3. Ultrasound-targeted microbubble destruction augmented synergistic therapy of rheumatoid arthritisviatargeted liposomes [J] . Wang Liyun, Zhu Bihui, Huang Jianbo, Journal of Materials Chemistry, B. materials for biology and medicine . 2020,第24期

机译：超声靶向微泡破坏增强了类风湿性关节炎脂质化脂质体的协同疗法
4. Image-guided doxorubicin delivery with ultrasound and microbubbles in a mouse model of hepatocellular carcinoma using a diagnostic ultrasound system [C] . Sara Keller, Dingjie Suo, Yak-Nam Wang, IEEE International Ultrasonics Symposium . 2019

机译：使用诊断超声系统使用诊断超声系统，在肝细胞癌小鼠模型中递送图像引导的多柔比星输送和微泡。
5. The Role of FOXO3 in Mechanisms of Doxorubicin Resistance in Hepatocellular Carcinoma [D] . Cox, Josiah. 2017

机译：FOXO3在肝细胞癌耐肠耐药机制中的作用
6. Ultrasound-Targeted Microbubble Destruction (UTMD) Combined with Liposome Increases the Effectiveness of Suppressing Proliferation Migration Invasion and Epithelial- Mesenchymal Transition (EMT) via Targeting Metadherin (MTDH) by ShRNA [O] . Juan Xu, Yeying Wang, Zhizheng Li, 2019

机译：超声靶向微泡破坏（UTMD）结合脂质体通过ShRNA靶向Metadherin（MTDH）增强抑制增殖迁移侵袭和上皮-间质转化（EMT）的有效性
7. Ultrasound-Targeted Microbubble Destruction (UTMD) Combined with Liposome Increases the Effectiveness of Suppressing Proliferation, Migration, Invasion, and Epithelial- Mesenchymal Transition (EMT) via Targeting Metadherin (MTDH) by ShRNA [O] . Juan Xu, Yeying Wang, Zhizheng Li, 2019

机译：超声靶向微泡破坏（UTMD）与脂质体相结合，增加了通过ShRNA靶向Metadherin（MTDH）的增殖，迁移，侵袭和上皮间过渡（EMT）的有效性

Effectiveness of localized ultrasound-targeted microbubble destruction with doxorubicin liposomes in H22 mouse hepatocellular carcinoma model

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