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首页> 外文期刊>Journal of drugs in dermatology: JDD >Treating hyperpigmentation in darker-skinned patients
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Treating hyperpigmentation in darker-skinned patients

机译:治疗肤色较黑的患者的色素沉着

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摘要

Background: The treatment of hyperpigmentation in darker-skinned patients (Fitzpatrick skin phototypes III-VI) has remained challenging for dermatologists. No studies have been conducted on hyperpigmentation under the eyes, axilla, and neck in darker-skinned patients. This survey was designed to assess current treatments of hyperpigmentation in these areas. Materials/Methods: With approval from the institutional review board at the University of California, Irvine, an electronic survey was sent to practicing dermatologists that contained 18 questions regarding the approach to evaluating and treating hyperpigmentation under the eyes, in the axilla, and along the neck. Results: Fifty dermatologists completed the survey, and 46 (92%) reported treating patients with darker skin. The ethnic groups treated were Latino (97.8%), African American (97.8%), Middle Eastern (77.6%), and Asian (88.9%). Thirty-six reported treating patients with hyperpigmentation under the eyes, and 22 (61.1%) thought the hyperpigmentation was a result of idiopathic increase in melanin deposition. Forty-two responded to treating hyperpigmentation in the axilla, most of whom thought it was related to acanthosis nigricans (69.0%) or contact dermatitis (59.5%). Forty responded to treating hyperpigmentation on the neck, most of whom treated the condition with hydroquinone (66%). Treatments for these 3 areas were not found to be effective. Conclusions: Hyperpigmentation under the eyes, under the arms, or on the neck is a significant problem in darker-skinned patients that is refractory to currently available treatments, highlighting the necessity of developing treatment approaches directed toward this population. Two cases of hyperpigmentation on the neck are presented, describing a new entity that primarily affects dark-skinned individuals.
机译:背景:皮肤较黑的患者(Fitzpatrick皮肤III型至VI型皮肤)色素沉着的治疗对皮肤科医生仍然具有挑战性。尚未对深色皮肤患者的眼睛,腋窝和颈部色素沉着过度进行过研究。这项调查旨在评估这些区域目前色素沉着过度的治疗方法。材料/方法:在加利福尼亚大学欧文分校的机构审查委员会的批准下,向从事皮肤病学的皮肤科医生发送了一份电子调查,其中包含18个问题,涉及评估和治疗眼下,腋下以及沿皮肤色素沉着过度的方法。颈部。结果:五十位皮肤科医生完成了调查,其中46位(92%)报告治疗皮肤深色的患者。所治疗的族裔是拉丁美洲人(97.8%),非洲裔美国人(97.8%),中东人(77.6%)和亚洲人(88.9%)。三十六例报告治疗眼下色素沉着过度的患者,有22名(61.1%)认为色素沉着过度是黑色素沉积特发性增加的结果。有42位患者对腋窝色素沉着的治疗有所反应,其中大多数人认为这与黑棘皮病(69.0%)或接触性皮炎(59.5%)有关。四十对治疗脖子上的色素沉着有反应,其中大多数用对苯二酚治疗(66%)。发现这三个区域的治疗无效。结论:在皮肤较黑的患者中,眼下,手臂下或脖子上的色素沉着是一个严重的问题,对于目前可用的治疗方法是无法解决的,这突出表明有必要针对该人群开发治疗方法。提出了两例颈部色素沉着过度的案例,描述了一个主要影响皮肤黝黑个体的新实体。

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