Synthesis, physicochemical characterization, and biological activity of nanocomplexes of iron(III) of 3(2'-hydroxyphenyl)-5-(4-substituted phenyl) pyrazolines and dithiophosphoric acid

摘要

Complexes of iron(III) with dithiophosphoric acid and 3(2'-hydroxy phenyl)-5-(4-substituted phenyl) pyrazolines, [Fe(C_6O_MO_2PS_2)2(C_(15)H_(12)N_2OX)], and [Fe(C_6O_(14)O_2PS_2)(C_(15)H_(15)N_2OX)_2], where (C_6O_(14)O_2PS_2H) = dithiophosphoric acid, (C_(15)H_(13)N_2OX) = deprotonated 3(2'-hydroxy phenyI)-5-(4-substituted phenyl)pyrazolines (X=H, CH_3, OCH_3, Cl), have been synthesized. These complexes have been physicochemically characterized by elemental analysis (C, H, N, S, Cl, and Fe), magnetic moment data, thermogravimetric analysis, molar conductance, cyclic voltammetry, and spectral analysis (UV-visible, IR, and Fast atom bombardment mass spectrometry). Scanning electron microscopy, TEM, and PXRD have been carried out for powdered samples, which show nanometric particles of these derivatives. Antibacterial and antifungal potential of free pyrazoline and iron(IIl) complexes have been evaluated.