Synthesis, characterization, and biological activity of nickel(II) complexes with a tridentate Schiff base derived from heterocyclic aldehyde

摘要

A series of nickel(II) complexes, namely [Ni(L)_2] (1), [Ni(L)(HL)](ClO_4)(H_2O) (2), [Ni(HL)(bipy)(H_2O)](NO_3)(ClO_4)(H_2O) (3). and lNi(HL)(dien)](ClO_4)_2(H_2O) (4) have been synthesized with Schiff base (L) derived from 2-pyridinecarboxaldehyde and benzoylhydrazine. The elemental analyses of the complexes indicate stoichiometry ML and M(L)(B), where L = N-[(l )-pyridin-2-ylmethyIidene]benzohydrazide, B = diethylenetriamine/2,2'-bipyridine. L is a deprotonated as well as neutral tridentate ligand. Single-crystal X-ray structures of 1-4 reveal distorted octahedral geometry in the complexes. The molecules are connected by various hydrogen-bonding interactions. Magnetic susceptibility measurements at room temperature were 2.79-2.91 MB. The electrochemical behavior, superoxide dismutasc, and antibacterial activities of these complexes were made by cyclic voltammetry, the alkaline DMSO-nitro blue tetrazolium chloride assay, and the paper disc diffusion method, respectively.