Characterization of temporal evolution of metabolic acidosis in adult patients with severe diabetic ketoacidosis admitted to the intensive care unit: Not quite done

摘要

We read with great interest the article by Lopes et al [1] describing, in a retrospective study, the characterization of temporal evolution of metabolic acidosis in adult patients with severe diabetic ketoacidosis (DKA) admitted to the intensive care unit by using the quantitative approach. We have some remarks regarding this article. We think that patients included in this study are not representative of patients with DKA, whom we can see admitted to intensive care unit, because they are not as severe as the authors pretend to be. Indeed, in accordance to the American Diabetes Association statements [2], the severity of DKA is classified as mild, moderate, or severe based on the severity of metabolic acidosis and the presence of altered mental status.