SIMULTANEOUS DETERMINATION OF A CAMPTOTHECIN DERIVATIVE, USED AS AN ANTICANCER DRUG, AND ITS PHOTODEGRADATION PRODUCTS BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY

Akimoto K; Kawai A; Ohya K

首页> 外文期刊>Journal of chromatography, A: Including electrophoresis and other separation methods >SIMULTANEOUS DETERMINATION OF A CAMPTOTHECIN DERIVATIVE, USED AS AN ANTICANCER DRUG, AND ITS PHOTODEGRADATION PRODUCTS BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY

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SIMULTANEOUS DETERMINATION OF A CAMPTOTHECIN DERIVATIVE, USED AS AN ANTICANCER DRUG, AND ITS PHOTODEGRADATION PRODUCTS BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY

机译：高效液相色谱法同时测定用作抗癌药的喜树碱衍生物及其光解产物

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A simple and rapid ion-pair high-performance liquid chromatographic method using a polymer-based column bonded octadecyl group was developed for the simultaneous determination of the anticancer drug CPT-11 and its three main photodegradation products. The analytes were detected by ultraviolet absorption at 254 nm.

机译：建立了一种基于聚合物的柱键联十八烷基的简单，快速的离子对高效液相色谱方法，用于同时测定抗癌药物CPT-11及其三种主要的光降解产物。通过254nm的紫外线吸收来检测分析物。

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《Journal of chromatography, A: Including electrophoresis and other separation methods》 |1996年第2期|共4页
作者
Akimoto K; Kawai A; Ohya K;
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正文语种 eng
中图分类仪器分析法（物理及物理化学分析法）;
关键词
Pharmaceutical analysis; Photodegradation; Cpt ii; Camptothecin; Acid;

机译：药物分析;光降解;Cpt ii;喜树碱;酸;

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专利

1. SIMULTANEOUS DETERMINATION OF A CAMPTOTHECIN DERIVATIVE, USED AS AN ANTICANCER DRUG, AND ITS PHOTODEGRADATION PRODUCTS BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY [J] . Akimoto K, Kawai A, Ohya K Journal of chromatography, A: Including electrophoresis and other separation methods . 1996,第2期

机译：高效液相色谱法同时测定用作抗癌药的喜树碱衍生物及其光解产物
2. Simultaneous determination of the lactone and carboxylate forms of the camptothecin derivative CPT-11 and its metabolite SN-38 in plasma by high-performance liquid chromatography [J] . Chollet DF., Renard A., Montay G., Journal of Chromatography, Biomedical Applications . 1998,第1期

机译：高效液相色谱法同时测定血浆中喜树碱衍生物CPT-11及其代谢产物SN-38的内酯和羧酸盐形式
3. Determination of the anticancer drug KW-2170, a pyrazoloacridone derivative, and its metabolites in human and dog plasma by high-performance liquid chromatography using an electrochemical detector [J] . Tomoko Kuramitsu, Katsumi Takai, Rui Ohashi, Journal of Chromatography, Biomedical Applications . 2002,第2期

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机译：使用基于微流体芯片的纳米液相色谱/四极其飞行时间和超高效液相色谱/串联质谱法进行验证的食品中的过敏原同时测定食品中的过敏原。
5. SIMULTANEOUS DETERMINATION OF PYRIDOXINE, RIBOFLAVIN, AND THIAMINE IN FORTIFIED CEREAL PRODUCTS BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (HPLC). [D] . WEHLING, RANDY LEE. 1983

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7. High-performance liquid chromatography and derivative spectrophotometry for simultaneous determination of pravastatin and fenofibrate in the dosage form [O] . HEFNAWY, MOHAMED M., MOHAMED, MOSTAFA S., ABOUNASSIF, MOHAMMED A., 2014

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8. Determination of 5-Dimethylaminonaphthalene-1-Sulfonyl Derivatives of Urinary Polyamines by Ion-Pair High-Performance Liquid Chromatography [R] . Brown, N. D., Sweet, R. B., Kintzios, J. A., 1979

机译：离子对高效液相色谱法测定尿多胺5-二甲基氨基萘-1-磺酰基衍生物

SIMULTANEOUS DETERMINATION OF A CAMPTOTHECIN DERIVATIVE, USED AS AN ANTICANCER DRUG, AND ITS PHOTODEGRADATION PRODUCTS BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY

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