Modified Rouchon and Rouchon-like algorithms for solving different models of multicomponent preparative chromatography

摘要

Modified Rouchon and Rouchon-like algorithms were used to solve multicomponent equilibrium-dispersive chromatographic models as well as a more general lumped pore diffusion model. The modified algorithms enable remarkable reduction of computation timeand avoid computation errors thai result from the original Rouchon approach for some cases of multicomponent chromatography. A comparison is given between the general chromatographic model, the lumped pore diffusion model and the equilibrium-dispersivemodel.