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Innovative accountability of tracking test kit as locked resources: A Lesson in a restricted resource setting

机译:跟踪测试套件作为锁定资源的创新责任制:受限资源设置中的一课

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Background: To implement quality screening in a blood service requires the presence of screening strategy with a clear algorithm and supporting standard operating procedures (SOPs), skilled and motivated human resource to perform testing, infrastructure, regular available test kits, and other supplies. In developing countries, smooth supply chain management of critical transfusion transmissible infections (TTIs) screening reagents is a challenge. Therefore, managing the little available kits by knowing the rate of consumption, good forecasting, and monitoring expiry date may be a key in ensuring regular supply. Method: Test kit monitoring tool (TKMT) for Vironostika HIV Uni-Form kit/192 1&2 Ag/Ab, Genedia kits for HBsAg and HCV, and RPR for syphilis was developed to track these reagents. This excel tool was developed to assess received reagents, quantity used, quantity remaining, and date of expiration. The tool was evaluated by assessing rerun for each test kits, match tests conducted with blood units tested, adherence to the principle of first in-first out (FIFO), and quantity remaining in the center against the need. Results: The mean rerun for HIV ELISA Vironistika uniform II Ag/Ab observed over expected was 6.9% (n = 3.8) than 2.4% (n = 1.3), HBsAg was 9.9% (n = 5.7) than 6.7% (3.5) (expected), Genedia for HCV was 1.3% (n = 0.7) than 0.5% (n = 0.3), and RPR test for syphilis 3.3% (n = 1.5) than 0.5%. During implementation, TKMT managed to detect expiring kits in the zonal blood transfusion centers. Conclusion: A tool-like TKMT may capture other supplies within blood when expanded. Monitoring of supplies may enable blood service actual accounting and in forecasting supplies and reagents.
机译:背景:要在血液服务中实施质量筛查,需要具有清晰算法和支持标准操作规程(SOP)的筛查策略,熟练且有动力的人力资源来执行检测,基础设施,定期可用的检测试剂盒和其他耗材。在发展中国家,关键输血传播感染(TTI)筛查试剂的顺利供应链管理是一个挑战。因此,通过了解消耗率,良好的预测并监控到期日期来管理少量可用的套件可能是确保定期供应的关键。方法:开发了用于Vironostika HIV Uni-form试剂盒/ 192 1&2 Ag / Ab的测试试剂盒监测工具(TKMT),用于HBsAg和HCV的Genedia试剂盒以及用于梅毒的RPR,以跟踪这些试剂。开发了该excel工具来评估收到的试剂,使用的数量,剩余数量和到期日期。通过评估每个测试套件的重新运行,与测试的血液单位进行的匹配测试,是否遵循先进先出(FIFO)原则以及是否需要保留在中心的数量,对工具进行了评估。结果:HIV ELISA Vironistika制服II Ag / Ab超出预期的平均重测率为6.9%(n = 3.8)比2.4%(n = 1.3),HBsAg为9.9%(n = 5.7)比6.7%(3.5)(预期),Genedia的HCV为1.3%(n = 0.7)比0.5%(n = 0.3),梅毒的RPR测试为3.3%(n = 1.5)比0.5%。在实施过程中,TKMT设法在区域输血中心检测到即将到期的试剂盒。结论:类似工具的TKMT在扩张时可能会捕获血液中的其他供应。供应的监视可以使血液服务能够进行实际核算以及预测供应和试剂。

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