OBJECTIVE: To evaluate the role of diffusion-weighted magnetic resonance (MR) imaging in the characterization of renal tumors. MATERIALS AND METHODS: Prospective study was conducted on 52 consecutive patients (24 males and 28 females) with renal tumor. They underwent diffusion-weighted echo planar MR imaging of the abdomen with b-factor of 0 and 800 seconds/mm(2). The apparent diffusion coefficient (ADC) value of the renal tumor was calculated and correlated with histopathological results. RESULTS: The mean ADC value of malignant renal tumors (1.56 +/- 0.26 x 10(3) mm(2)/s) was significantly different (P = 0.001) from that of benign tumors (1.87 +/- 0.50 x 10(3) mm(2)/s). Selection of 1.84 x 10(3) mm(2)/s as a cutoff point of ADC value to predict renal malignancy revealed accuracy of 89%, sensitivity of 89%, and specificity of 89%. The cutoff point of ADC value to differentiate renal cell carcinoma (RCC) from other malignancy (1.15 x 10(3) mm(2)/s) revealed 72% accuracy, 95% sensitivity, 50% specificity. The cutoff point of ADC value used to differentiate clear and papillary RCC from other subtypes of RCC was 1.84 x 10(3) mm(2)/s with an accuracy of 89%, sensitivity of 89%, and specificity of 89%. CONCLUSION: Apparent diffusion coefficient value can differentiate benign from malignant renal tumors and may be helpful for the differentiation of the histologic subtypes of RCC.
展开▼
机译：目的：评估弥散加权磁共振（MR）成像在肾肿瘤表征中的作用。材料与方法：前瞻性研究连续52例肾肿瘤患者（男24例，女28例）进行了研究。他们接受了b因子为0和800秒/ mm（2）的腹部扩散加权回声平面MR成像。计算肾肿瘤的表观扩散系数（ADC）值，并将其与组织病理学结果相关联。结果：恶性肾肿瘤的ADC平均值（1.56 +/- 0.26 x 10（3）mm（2）/ s）与良性肿瘤的ADC平均值（1.87 +/- 0.50 x 10（s）显着不同（P = 0.001） 3）mm（2）/ s）。选择1.84 x 10（3）mm（2）/ s作为ADC值的临界点以预测肾恶性，显示准确性为89％，敏感性为89％，特异性为89％。区分肾细胞癌（RCC）与其他恶性肿瘤（1.15 x 10（3）mm（2）/ s）的ADC值的临界点显示出72％的准确性，95％的敏感性和50％的特异性。用于区分透明和乳头状RCC与其他亚型RCC的ADC值的临界点为1.84 x 10（3）mm（2）/ s，准确度为89％，灵敏度为89％，特异性为89％。结论：表观扩散系数值可区分良性和恶性肾肿瘤，可能有助于区分RCC的组织学亚型。
展开▼
