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Concealed allocation: an under-reported and misunderstood component of trial methodology in stroke rehabilitation - reply

机译:隐蔽分配:中风康复试验方法中未充分报告和误解的部分-答复

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摘要

We would like to thank Drs. Berger and Do [1] for making us aware of Berger's work, which includes approaches for the prevention, detection, and statistical adjustment of the effects of third-order residual selection bias because of lack of concealed allocation (CA) in randomized trials [2]. Having now acquainted ourselves with his work, we believe that our two groups probably share many values and beliefs. At a general level, we share a profound respect for the scientific method, including the necessity of observing proper methodology. More specifically, we share an interest in the problematic issue of CA in clinical trials. And finally, we would likely agree that CA is frequently misunderstood by authors and, by implication, editors and reviewers.
机译:我们要感谢博士。 Berger和Do [1]使我们了解了Berger的工作,其中包括预防,检测和统计调整由于随机试验中缺乏隐蔽分配(CA)而导致的三阶残留选择偏倚的影响的方法[2]。 ]。现在,我们熟悉了他的工作,我们认为我们两个小组可能具有许多价值观和信念。从总体上讲,我们对科学方法深有同感,包括遵守正确方法的必要性。更具体地说,我们在临床试验中对有问题的CA感兴趣。最后,我们可能会同意,作者,作者和编辑和审阅者经常会误解CA。

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